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Title: Mmpip  
Author: World Heritage Encyclopedia
Language: English
Subject: A.C.E. mixture, LY-344,545, EGLU, LY-307,452, PCCG-4
Collection: Mglu7 Receptor Antagonists, Receptor Antagonists
Publisher: World Heritage Encyclopedia


Systematic (IUPAC) name
Clinical data
Legal status
ATC code ?
Chemical data
Formula C19H19N3O3 
Mol. mass 337.372 g/mol

MMPIP is a drug used in scientific research that acts as a selective antagonist for the metabotropic glutamate receptor subtype mGluR7.[1] This receptor subtype appears to be involved in the downstream response to cocaine in the brain.[2]


  1. ^ Suzuki G, Tsukamoto N, Fushiki H, Kawagishi A, Nakamura M, Kurihara H, Mitsuya M, Ohkubo M, Ohta H (October 2007). "In vitro pharmacological characterization of novel isoxazolopyridone derivatives as allosteric metabotropic glutamate receptor 7 antagonists". The Journal of Pharmacology and Experimental Therapeutics 323 (1): 147–56.  
  2. ^ Li X, Li J, Peng XQ, Spiller K, Gardner EL, Xi ZX (June 2009). "Metabotropic glutamate receptor 7 modulates the rewarding effects of cocaine in rats: involvement of a ventral pallidal GABAergic mechanism". Neuropsychopharmacology 34 (7): 1783–96.  

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