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Review of Scientific Instruments : Microbeam-integrated multiphoton imaging system

By Alan W. Bigelow, Charles R. Geard, Gerhard Randers-Pehrson, and David J. Brenner

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Book Id: WPLBN0002169701
Format Type: PDF eBook :
File Size: Serial Publication
Reproduction Date: 12 December 2008

Title: Review of Scientific Instruments : Microbeam-integrated multiphoton imaging system  
Author: Alan W. Bigelow, Charles R. Geard, Gerhard Randers-Pehrson, and David J. Brenner
Volume: Issue : December 2008
Language: English
Subject: Science, Physics, Natural Science
Collections: Periodicals: Journal and Magazine Collection (Contemporary), Review of Scientific Instruments Collection
Historic
Publication Date:
Publisher: American Institute of Physics

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Bigelow, Charles R. Geard, Gerhard Randers-Pehrson, And David J. Brenne, A. W. (n.d.). Review of Scientific Instruments : Microbeam-integrated multiphoton imaging system. Retrieved from http://worldebookfair.com/


Description
Description: Multiphoton microscopy has been added to the array of imaging techniques at the endstation for the Microbeam II cell irradiator at Columbia University’s Radiological Research Accelerator Facility (RARAF). This three-dimensional (3D), laser-scanning microscope functions through multiphoton excitation, providing an enhanced imaging routine during radiation experiments with tissuelike samples, such as small living animals and organisms. Studies at RARAF focus on radiation effects; hence, this multiphoton microscope was designed to observe postirradiation cellular dynamics. This multiphoton microscope was custom designed into an existing Nikon Eclipse E600-FN research fluorescence microscope on the irradiation platform. Design details and biology applications using this enhanced 3D-imaging technique at RARAF are reviewed.

 

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