World Library  


Add to Book Shelf
Flag as Inappropriate
Email this Book

Plos One : Exploring Angular Distance in Protein-protein Docking Algorithms, Volume 7

By Zhang, Yang

Click here to view

Book Id: WPLBN0003937426
Format Type: PDF eBook :
File Size:
Reproduction Date: 2015

Title: Plos One : Exploring Angular Distance in Protein-protein Docking Algorithms, Volume 7  
Author: Zhang, Yang
Volume: Volume 7
Language: English
Subject: Journals, Science, Medical Science
Collections: Periodicals: Journal and Magazine Collection
Historic
Publication Date:
Publisher: Plos

Citation

APA MLA Chicago

Zhang, Y. (n.d.). Plos One : Exploring Angular Distance in Protein-protein Docking Algorithms, Volume 7. Retrieved from http://worldebookfair.com/


Description
Description : We present a two-stage hybrid-resolution approach for rigid-body protein-protein docking. The first stage is carried out at low-resolution (15u) angular sampling. In the second stage, we sample promising regions from the first stage at a higher resolution of 6u. The hybrid-resolution approach produces the same results as a 6u uniform sampling docking run, but uses only 17% of the computational time. We also show that the angular distance can be used successfully in clustering and pruning algorithms, as well as the characterization of energy funnels. Traditionally the root-mean-square-distance is used in these algorithms, but the evaluation is computationally expensive as it depends on both the rotational and translational parameters of the docking solutions. In contrast, the angular distances only depend on the rotational parameters, which are generally fixed for all docking runs. Hence the angular distances can be pre-computed, and do not add computational time to the post-processing of rigid-body docking results.

 

Click To View

Additional Books


  • Plos One : Effet of Combined Nitrogen Di... (by )
  • Plos One : the Conserved Residue Arg46 i... (by )
  • Plos One : the Observed Association Betw... (by )
  • Plos One : Agent of Whirling Disease Mee... (by )
  • Plos One : Differential Dynamics of Tran... (by )
  • Plos One : Levels of Tuberculosis Treatm... (by )
  • Plos One : New Australovenator Hind Limb... (by )
  • Plos One : Bacterial Cyclic Amp-phosphod... (by )
  • Plos One : Cyp2J2 Overexpression Protect... (by )
  • Plos One : Granulocyte Colony Stimulatin... (by )
  • Plos One : Intranasal Delivery of Plasma... (by )
  • Plos One : Quantitative Susceptibility M... (by )
Scroll Left
Scroll Right

 



Copyright © World Library Foundation. All rights reserved. eBooks from World eBook Fair are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.