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Plos One : Mutations in Lmna Modulate the Lamin a - Nesprin-2 Interaction and Cause Linc Complex Alterations, Volume 8

By Lewin, Alfred

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Book Id: WPLBN0003963611
Format Type: PDF eBook :
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Reproduction Date: 2015

Title: Plos One : Mutations in Lmna Modulate the Lamin a - Nesprin-2 Interaction and Cause Linc Complex Alterations, Volume 8  
Author: Lewin, Alfred
Volume: Volume 8
Language: English
Subject: Journals, Science, Medical Science
Collections: Periodicals: Journal and Magazine Collection (Contemporary)
Historic
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Publisher: Plos

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Lewin, A. (n.d.). Plos One : Mutations in Lmna Modulate the Lamin a - Nesprin-2 Interaction and Cause Linc Complex Alterations, Volume 8. Retrieved from http://worldebookfair.com/


Description
Description : Mutations in Nesprin-2 and lamin A are characterised by complex genotype phenotype relations. Our data show that each mutation in LMNAanalysed here has a distinct impact on the interaction among both proteins that substantially explains how distinct mutations in widely expressed genes lead to the formation of phenotypically different diseases.

 

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