World Library  


Add to Book Shelf
Flag as Inappropriate
Email this Book

Plos One : Robust and Highly-efficient Differentiation of Functional Monocytic Cells from Human Pluripotent Stem Cells Under Serum- and Feeder Cell-free Conditions, Volume 8

By Aalto-setala, Katriina

Click here to view

Book Id: WPLBN0003966209
Format Type: PDF eBook :
File Size:
Reproduction Date: 2015

Title: Plos One : Robust and Highly-efficient Differentiation of Functional Monocytic Cells from Human Pluripotent Stem Cells Under Serum- and Feeder Cell-free Conditions, Volume 8  
Author: Aalto-setala, Katriina
Volume: Volume 8
Language: English
Subject: Journals, Science, Medical Science
Collections: Periodicals: Journal and Magazine Collection
Historic
Publication Date:
Publisher: Plos

Citation

APA MLA Chicago

Aalto-Setala, K. (n.d.). Plos One : Robust and Highly-efficient Differentiation of Functional Monocytic Cells from Human Pluripotent Stem Cells Under Serum- and Feeder Cell-free Conditions, Volume 8. Retrieved from http://worldebookfair.com/


Description
Description : Monocytic lineage cells (monocytes, macrophages and dendritic cells) play important roles in immune responses and are involved in various pathological conditions. The development of monocytic cells from human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) is of particular interest because it provides an unlimited cell source for clinical application and basic research on disease pathology. Although the methods for monocytic cell differentiation from ESCs/ iPSCs using embryonic body or feeder co-culture systems have already been established, these methods depend on the use of xenogeneic materials and, therefore, have a relatively poor-reproducibility. Here, we established a robust and highlyefficient method to differentiate functional monocytic cells from ESCs/iPSCs under serum- and feeder cell-free conditions. This method produced 1.3610660.36106 floating monocytes from approximately 30 clusters of ESCs/iPSCs 5–6 times per course of differentiation. Such monocytes could be differentiated into functional macrophages and dendritic cells. This method should be useful for regenerative medicine, disease-specific iPSC studies and drug discovery.

 

Click To View

Additional Books


  • Plos One : Inhibition of Tankyrases Indu... (by )
  • Plos One : Glutamate Transporters Eaat4 ... (by )
  • Plos One : Cardiac Gene Activation Analy... (by )
  • Plos One : Identification of the Immunog... (by )
  • Plos One : Effects of L-dopa During Audi... (by )
  • Plos One : Pathogenic Mouse Hepatitis Vi... (by )
  • Plos One : Cloning and Characterization ... (by )
  • Plos One : Involvement of Micrornas in R... (by )
  • Plos One : Gelam Honey Attenuates Carrag... (by )
  • Plos One : Immunization with a Hemagglut... (by )
  • Plos One : Fixational Eye Movements in t... (by )
  • Plos One : Characterization of Protectiv... (by )
Scroll Left
Scroll Right

 



Copyright © World Library Foundation. All rights reserved. eBooks from World eBook Fair are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.