World Library  

Add to Book Shelf
Flag as Inappropriate
Email this Book

Plos One : the Dental Plaque Microbiome in Health and Disease, Volume 8

By Highlander, Sarah K.

Click here to view

Book Id: WPLBN0003967813
Format Type: PDF eBook :
File Size:
Reproduction Date: 2015

Title: Plos One : the Dental Plaque Microbiome in Health and Disease, Volume 8  
Author: Highlander, Sarah K.
Volume: Volume 8
Language: English
Subject: Journals, Science, Medical Science
Collections: Periodicals: Journal and Magazine Collection (Contemporary)
Publication Date:
Publisher: Plos


APA MLA Chicago

Highlander, S. K. (n.d.). Plos One : the Dental Plaque Microbiome in Health and Disease, Volume 8. Retrieved from

Description : Dental decay is one of the most prevalent chronic diseases worldwide. A variety of factors, including microbial, genetic, immunological, behavioral and environmental, interact to contribute to dental caries onset and development. Previous studies focused on the microbial basis for dental caries have identified species associated with both dental health and disease. The purpose of the current study was to improve our knowledge of the microbial species involved in dental caries and health by performing a comprehensive 16S rDNA profiling of the dental plaque microbiome of both caries-free and caries-active subjects. Analysis of over 50,000 nearly full-length 16S rDNA clones allowed the identification of 1,372 operational taxonomic units (OTUs) in the dental plaque microbiome. Approximately half of the OTUs were common to both caries-free and caries-active microbiomes and present at similar abundance. The majority of differences in OTU’s reflected very low abundance phylotypes. This survey allowed us to define the population structure of the dental plaque microbiome and to identify the microbial signatures associated with dental health and disease. The deep profiling of dental plaque allowed the identification of 87 phylotypes that are over-represented in either caries-free or caries-active subjects. Among these signatures, those associated with dental health outnumbered those associated with dental caries by nearly two-fold. A comparison of this data to other published studies indicate significant heterogeneity in study outcomes and suggest that novel approaches may be required to further define the signatures of dental caries onset and progression.


Click To View

Additional Books

  • Plos One : N-terminal Region of Gelsolin... (by )
  • Plos One : Rebmab200, a Humanized Monocl... (by )
  • Plos One : Advanced Mathematical Study a... (by )
  • Plos One : Deficiency of Interleukin-15 ... (by )
  • Plos One : the Inhibition of Autophagy S... (by )
  • Plos One : Evolutionary Dynamics of Micr... (by )
  • Plos One : the Novel Pro-osteogenic Acti... (by )
  • Plos One : Atomic Hydrogen Surrounded by... (by )
  • Plos One : Wnt10A Plays an Oncogenic Rol... (by )
  • Plos One : Overexpression of Myrakt1 in ... (by )
  • Plos One : Association of Snp Rs6903956 ... (by )
  • Plos One : Heat Shock Protein 27 is Spat... (by )
Scroll Left
Scroll Right


Copyright © World Library Foundation. All rights reserved. eBooks from World eBook Fair are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.