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Plos One : the Relative Contribution of Paracine Effect Versus Direct Differentiation on Adipose-derived Stem Cell Transplantation Mediated Cardiac Repair, Volume 8

By Qin, Gangjian

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Book Id: WPLBN0003968413
Format Type: PDF eBook :
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Reproduction Date: 2015

Title: Plos One : the Relative Contribution of Paracine Effect Versus Direct Differentiation on Adipose-derived Stem Cell Transplantation Mediated Cardiac Repair, Volume 8  
Author: Qin, Gangjian
Volume: Volume 8
Language: English
Subject: Journals, Science, Medical Science
Collections: Periodicals: Journal and Magazine Collection (Contemporary)
Historic
Publication Date:
Publisher: Plos

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Qin, G. (n.d.). Plos One : the Relative Contribution of Paracine Effect Versus Direct Differentiation on Adipose-derived Stem Cell Transplantation Mediated Cardiac Repair, Volume 8. Retrieved from http://worldebookfair.com/


Description
Description : ADSC-CM is sufficient to improve cardiac function of infarcted hearts. The therapeutic function of ADSC transplantation is mainly induced by paracrine-mediated cardioprotection and angiogenesis, while ADSC differentiation contributes a minor benefit by being involved in angiogenesis. Highlights 1 ADSC-CM is sufficient to exert a therapeutic potential. 2. ADSC was able to differentiate to vascular cells but not cardiomyocyte. 3. ADSC derived vascular cells amount to about 9% of the enhanced angiogenesis. 4. Paracrine effect is the major mechanism of ADSC therapeutic function for MI.

 

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